Dr Eli

Longevity supplements from Switzerland.

“I trust Avea because they don’t just follow trends, they follow the science. Their formulations are thoughtful, clinically backed, and aligned with the future of personalized longevity. In a world full of noise, Avea brings clarity.”

"I trust Avea because they don’t just follow trends, they follow the science. Their formulations are thoughtful, clinically backed, and aligned with the future of personalized longevity. In a world full of noise, Avea brings clarity."

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AVEA's formulations are developed and continuously refined in collaboration with experienced scientists, doctors, and nutrition professionals from leading institutions. This sound, scientifically based approach ensures that AVEA plays a pioneering role in longevity research and always remains at the cutting edge of science.

Deep, Natural Sleep

sereniser

As we age, our sleep architecture naturally begins to shift. Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep, making making sleep more fragmented and less restorative, even if you’re getting enough hours.

The Sereniser is AVEA'S hormone-free, science-backed approach to deeper, more restorative sleep. Unlike most sleep supplements that rely on melatonin or sedatives to force sleep, we intentionally designed Sereniser to support your body’s natural sleep-wake cycle, without disrupting your hormones, creating dependency, or leaving you drowsy the next day.

How does the Sereniser work differently?

A hormone-free, science-backed approach to deeper, more restorative sleep.

Unlike most sleep supplements that rely on melatonin or sedatives to force sleep, we intentionally designed Sereniser to support your body’s natural sleep-wake cycle – without disrupting your hormones, creating dependency, or leaving you drowsy the next day.

Formulated with leading longevity researchers in Switzerland, it takes a multi-pathway approach grounded in neuroscience, adaptogens, and chronobiology. Each ingredient was selected for its ability to target key systems involved in high-quality sleep – mood regulation, cortisol balance, circadian rhythm, and sleep architecture – without interfering with your body's natural rhythms.

What makes the Sereniser different:

1. Calms the body and mind

The Sereniser helps ease the physiological and mental tension that can keep you alert, even when you feel tired.

L-Theanine – Promotes calming alpha brain waves to create a relaxed, pre-sleep mental state.
Holixer® (Holy Basil) – A clinically studied adaptogen shown to reduce cortisol levels and improve resilience to nighttime stress.
Safr’Inside™ (Saffron extract) – Enhances serotonin activity to improve pre-sleep mood, reduce anxiety, and promote natural relaxation.

2. Supports deep, uninterrupted sleep
Rather than simply sedating the brain, Sereniser helps the body reach and maintain deep, restorative sleep stages.

Serezin™ (Ginger + Frankincense) – A patented plant-based complex that reduces inflammation-related discomfort and nighttime awakenings.
Magnesium Bisglycinate – A gentle, more bioavailable form of magnesium that relaxes muscles and the nervous system to reduce tossing and turning.
Vitamin B6 + Safr’Inside™ – Together support the natural production of melatonin and GABA, promoting continuous, undisturbed sleep.

3. Balances your internal cycle

Rather than flooding the system with synthetic melatonin, Sereniser helps regulate your body's own circadian rhythm to promote consistency and better mornings.

Holixer® – supports healthy cortisol patterns, helping the body wind down more easily in the evening.
Safr’Inside™ – enhances serotonin-to-melatonin conversion for smoother transitions into sleep.
Vitamin B6 & Magnesium – help reinforce steady sleep patterns by supporting GABA and neurotransmitter balance.

4. Non-habit forming & melatonin-free

Many sleep supplements rely on synthetic melatonin, which can disrupt your natural rhythm and lead to dependency over time. Sereniser takes a more natural, longer-term approach:

No hormonal interference
No tolerance build-up over time
No residual drowsiness or sedation the next day

Just deep, consistent rest - the way your body was designed to experience it.

Why melatonin and conventional sleep aids may be doing more harm than good

To counter these changes, many people turn to over-the-counter melatonin or prescription sedatives (often referred to as sleeping pills) or antihistamines.

But most of these solutions work by artificially sedating the brain, and may cause more harm than good – particularly as we age.

Melatonin is a hormone your brain produces in response to darkness. It signals that it’s time to wind down – but it doesn’t control how long you sleep or how deeply you rest. When taken in high doses, at the wrong time, or for extended periods, melatonin can:

Disrupt your body’s natural melatonin production
Disrupt your internal sleep-wake rhythm even further
Cause residual drowsiness, vivid dreams, or headaches over time

Sedatives go a step further by suppressing brain activity altogether – inducing unconsciousness, but not true sleep. These drugs can interrupt your brain’s natural sleep architecture, preventing you from reaching slow-wave and REM sleep – the very stages responsible for memory consolidation, emotional regulation, and immune function.

Over time, the use of sedatives has also been linked to increased risk of cognitive decline, particularly in older adults.

Instead of forcing sleep, the goal should be to support the systems that naturally regulate it – including your circadian rhythm, nervous system, cortisol cycles, and neurotransmitters like GABA and serotonin.

This is what allows the body to access real, uninterrupted sleep and with it, the recovery, clarity, and long-term resilience it was designed for.

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Increased, Sustained Energy

vitality bundle

Every cell in your body relies on NAD+ (nicotinamide adenine dinucleotide) – a coenzyme that fuels energy production, supports metabolism, and keeps your body running at its best. A well-supported NAD+ system is linked to:

Sustained energy throughout the day
Sharper focus and mental clarity
Improved metabolism and endurance
Cellular repair, recovery, and longevity

But as you age, NAD+ levels decline, leading to fatigue, slower recovery, and reduced cognitive function. Our unique Vitality Bundle is your tool to retain your NAD+ levels in the most effective way – by not only replenishing NAD+, but also enhancing mitochondrial function and slowing NAD+ breakdown.

Why does NAD+ decline and what happens when it does?

From your 30s onward, NAD+ levels begin to decline, dropping by nearly 50% by middle age. The exact reasons for this decline are not fully understood yet but seems to be linked to the decreased ability of the body to convert nutrients in food to NAD+.

This natural decrease slows down your body's ability to produce energy and repair itself, leading to:

Fatigue and reduced endurance – making it harder to stay active
Slower metabolism and recovery – impacting fitness and weight management
Brain fog and mental fatigue – decreasing focus and cognitive sharpness
Weakened cellular repair – accelerating signs of ageing

This decline isn’t just about feeling tired – it affects your body at a cellular level, reducing mitochondrial efficiency (your body’s energy powerhouse) and making you more susceptible to stress, inflammation, and ageing.

What to look for to support your NAD+ levels?

Supplementing with NMN (nicotinamide mononucleotide), a direct precursor to NAD+, has been shown to significantly restore levels in key tissues like the brain, muscles, and heart.

But what many people overlook is that NMN is only part of the equation. To truly maintain NAD+ levels over time, your body also needs the right co-factors to support its production, recycling, and protection.

That’s why a multi-targeted approach delivers better results – by not only replenishing NAD+, but also enhancing mitochondrial function and slowing down NAD+ breakdown

To make this possible, we created the Vitality Bundle, a two-part system designed to restore, sustain, and protect NAD+ levels at the cellular level:

NMN – NAD+ precursor efficiently converted into NAD+ to restore cellular energy, metabolism, and endurance

Booster – contains synergistic ingredients to enhance and sustain NAD+:

Resveratrol and Pterostilbene help your cells produce more mitochondria, the power plants of your cells, while CoQ10 boosts their efficiency, together increasing energy output.
Betaine supports methylation, a key process that influences NAD+ metabolism and recycling, ensuring efficient conversion of NMN to NAD+.
Apigenin inhibits CD38, an enzyme that breaks down NAD+, thereby helping your body make more use of its existing NAD+.

Together, they create a powerful foundation for sustained energy, faster recovery, and cellular longevity.

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Better Skin, Hair & Nails

collagen activator

Traditional collagen products often rely on hydrolysed animal collagen: large protein fragments that must be broken down and absorbed before they can be used by the body. While these peptides can provide raw materials, their biological impact is limited as the body doesn’t automatically recognise them as a signal to produce more collagen, and in many cases, they are diverted to other functions like general protein metabolism - offering little benefit to the skin.

We developed the Collagen Activator to address this key limitation in the collagen supplement space, and instead of relying on passive replacement, our formula is designed to actively stimulate the body’s own collagen-building processes.

Created in collaboration with longevity researchers and scientists from ETH Zurich, the Collagen Activator features Colgevity™ - our 100% vegan, patented formula clinically shown to be up to 4x more effective than standard collagen supplements¹. It combines a precise ratio of amino acids with targeted co-factors to drive endogenous collagen production.

Why most collagen supplements are not effective for true collagen synthesis, and what is actually needed

Collagen is one of the most vital structural proteins in the body, responsible for keeping skin firm, elastic, and resilient. Yet most collagen supplements fail to deliver meaningful results - not because collagen doesn’t matter, but because the way it’s supported matters even more.

Traditional collagen products often rely on hydrolysed animal collagen: large protein fragments that must be broken down and absorbed before they can be used by the body. While these peptides can provide raw materials, their biological impact is limited as the body doesn’t automatically recognise them as a signal to produce more collagen, and in many cases, they are diverted to other functions like general protein metabolism, offering little benefit to the skin.

To effectively stimulate collagen renewal, the body needs more than just raw protein. Collagen synthesis is a complex biological process that requires:

Precise amino acids:
Collagen is primarily built from three key amino acids: glycine, proline, and hydroxyproline. These must be delivered in the right ratio and form to be recognised as collagen-building material. Generic protein or random peptides won’t achieve the same result.

A biological signal to activate production
Collagen is produced by fibroblasts, which are specialised skin cells that require a biological signal to initiate synthesis. Without this signal, the body has no reason to begin building new collagen, even if the raw materials are present.

Cofactors that stabilise and support synthesis
Nutrients such as vitamin C and Alpha-Ketoglutarate (AKG) are essential for the enzymatic processes that link collagen fibres and stabilise the matrix.

Without them, collagen strands remain weak, disorganised, and prone to breakdown.

When these components are missing or imbalanced, the body lacks both the building blocks and the biological instructions needed to produce strong, stable collagen. This is where many supplements fall short - they may supply fragments but fail to engage the skin’s natural regeneration process.

How the Collagen Activator works, and why it’s different from other collagen supplements

We developed the Collagen Activator to address a key limitation in the collagen supplement space: most formulas simply deliver fragmented, animal-derived collagen without addressing whether the body can use it. Instead of relying on passive replacement, our formula is designed to actively stimulate the body’s own collagen-building processes.

Created in collaboration with longevity researchers and scientists from ETH Zurich, the Collagen Activator features Colgevity™ - our 100% vegan, patented formula clinically shown to be up to 4x more effective than standard collagen supplements¹. It combines a precise ratio of amino acids with targeted co-factors to drive endogenous collagen production - helping to rebuild the structural proteins that keep skin firm, smooth, and elastic.

And unlike traditional supplements that use hydrolysed collagen from animal sources, the Collagen Activator works across multiple biological pathways to support natural collagen synthesis at the cellular level:

For replenishing diminishing collagen levels
The foundation of the formula is Colgevity™ - a patented vegan collagen precursor that provides the three key amino acids (glycine, proline, and hydroxyproline) in the precise ratio needed for collagen synthesis. Unlike hydrolysed collagen, which is often broken down before reaching the skin, these building blocks are readily used by fibroblasts to produce new collagen more efficiently, thus helping restore skin volume, structure, and strength.

For boosting skin elasticity & hydration
Acerola cherry extract, a potent natural source of vitamin C, supports collagen cross-linking and protects skin cells from oxidative damage. Together with Alpha-Ketoglutarate (AKG) - a longevity compound that fuels cellular repair - this duo helps improve skin’s elasticity, promote smoother texture, and restore hydration balance at the structural level.

For enhancing skin firmness and reducing fine lines
As collagen production slows, skin begins to lose its firmness and smooth appearance. The Collagen Activator works to restore dermal density by stimulating natural collagen synthesis and reducing inflammation - two critical processes for maintaining tone and preventing the formation of fine lines. The result: visibly firmer, more youthful-looking skin over time.

For strengthening hair and nails
The Collagen Activator provides key amino acids such as Proline, which not only support collagen formation but also contribute to the structure of keratin-rich tissues like hair and nails.

Combined with nutrients that enhance tissue repair and integrity, it promotes visibly stronger, less brittle nails and thicker, shinier hair, thus offering a holistic approach to beauty and structural health.

shop now - €71,10

Our science team

At Avea, every ingredient, form, and formulation is obsessively researched by our in-house team of scientists and researchers.

learn more

Sophie Chabloz

Chief Science Officer

Prof. Colin Ewald

Scientist & Professor,
ETH Zurich

Dr. med. Shirin Hund

Scientific Advisor

Dr. med. Andrea Gartenbach

Scientific Advisor

Dr. med. Manuel Puntschuh

Scientific Advisor

Dr. Soheil Saeedi Saravi, PharmD, PhD

Scientific Advisor

Dr. Matilde Mantovani

Molecular Biologist

Nicolas Ting

Nutrition Scientist

Simran Rajarai

Biochemist

Aratsu Sharma

Neuroscientist