4.7/5 based on over 700 ratings
The Sereniser is your non-hormonal solution to truly restorative sleep – helping you fall asleep faster, stay asleep longer, and wake up clear-headed and energised. Its clinically studied ingredients calm the mind, promote deeper, uninterrupted sleep, and regulate natural sleep cycles, ensuring you wake up recharged and ready for the day.
Unlike most sleep supplements that rely on melatonin or sedatives to force sleep, we intentionally designed our Sereniser to support your body’s natural sleep-wake cycle.
Developed with longevity researchers in Switzerland, it takes a multi-pathway approach grounded in neuroscience and chronobiology to support mood, cortisol balance, circadian rhythm, and deep sleep architecture – all without disrupting your body’s natural rhythms.
This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress².
This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress².
Holixer® helps regulate cortisol levels, while Safr’Inside™ improves sleep quality and reduces stress. Together, they naturally support the body’s circadian rhythm and the natural melatonin production. Magnesium and Vitamin B6 support GABA activity – helping you fall asleep and wake in better alignment with your body’s natural rhythm – without external melatonin.
Sereniser combines Serezin™, Magnesium Glycinate, and Vitamin B6 + Safr’Inside™ to support all phases of sleep – from onset to deep rest. Serezin™ helps reduce nighttime discomfort, Magnesium Glycinate relaxes muscles and nerves, while B6 and Safr’Inside™ promote natural melatonin production – supporting deeper, more restorative sleep and improved next-day focus.
Sereniser combines Serezin™, Magnesium Glycinate, and Vitamin B6 + Safr’Inside™ to support all phases of sleep – from onset to deep rest. Serezin™ helps reduce nighttime discomfort, Magnesium Glycinate relaxes muscles and nerves, while B6 and Safr’Inside™ promote natural melatonin production – supporting deeper, more restorative sleep and improved next-day focus.
Unlike sedatives, Sereniser promotes restorative sleep without morning drowsiness or dependency. Serezin™ has been clinically shown to improve sleep quality and morning alertness³ – helping you wake up clear, refreshed, and ready to start the day with focus, energy, and a greater sense of mental and physical well-being.
This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress².
Holixer® helps regulate cortisol levels, while Safr’Inside™ improves sleep quality and reduces stress. Together, they naturally support the body’s circadian rhythm and the natural melatonin production. Magnesium and Vitamin B6 support GABA activity – helping you fall asleep and wake in better alignment with your body’s natural rhythm – without external melatonin.
Sereniser combines Serezin™, Magnesium Glycinate, and Vitamin B6 + Safr’Inside™ to support all phases of sleep – from onset to deep rest. Serezin™ helps reduce nighttime discomfort, Magnesium Glycinate relaxes muscles and nerves, while B6 and Safr’Inside™ promote natural melatonin production – supporting deeper, more restorative sleep and improved next-day focus.
Unlike sedatives, Sereniser promotes restorative sleep without morning drowsiness or dependency. Serezin™ has been clinically shown to improve sleep quality and morning alertness³ – helping you wake up clear, refreshed, and ready to start the day with focus, energy, and a greater sense of mental and physical well-being.
This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress².
Holixer® helps regulate cortisol levels, while Safr’Inside™ improves sleep quality and reduces stress. Together, they naturally support the body’s circadian rhythm and the natural melatonin production. Magnesium and Vitamin B6 support GABA activity – helping you fall asleep and wake in better alignment with your body’s natural rhythm – without external melatonin.
Sereniser combines Serezin™, Magnesium Glycinate, and Vitamin B6 + Safr’Inside™ to support all phases of sleep – from onset to deep rest. Serezin™ helps reduce nighttime discomfort, Magnesium Glycinate relaxes muscles and nerves, while B6 and Safr’Inside™ promote natural melatonin production – supporting deeper, more restorative sleep and improved next-day focus.
Unlike sedatives, Sereniser promotes restorative sleep without morning drowsiness or dependency. Serezin™ has been clinically shown to improve sleep quality and morning alertness³ – helping you wake up clear, refreshed, and ready to start the day with focus, energy, and a greater sense of mental and physical well-being.
The Sereniser gently calms your nervous system and eases mental tension, helping you fully unwind and drift off into restful sleep with ease.
Do you often wake up in the middle of the night? The Sereniser supports uninterrupted, restorative sleep by reducing restlessness and enhancing deep sleep cycles.
With deeper, more consistent sleep each night, you’ll start your day with steady energy, better focus, and a clearer mind.
Whether you're dealing with late nights, jet lag, or inconsistent routines, the Sereniser helps restore a healthy sleep-wake cycle.
From stress and screen time to irregular schedules, the Sereniser targets the root causes of poor sleep in today’s world.
Sleep is not just about duration – it’s about depth, cycles, and consistency.
Most of us know we need 7–9 hours of sleep, but not all sleep is created equal.
Throughout the night, your brain moves through a series of stages—light sleep, deep sleep (also known as slow-wave sleep), and REM sleep (when most dreaming occurs). These stages cycle roughly every 90 minutes and each plays a distinct role in how your body and mind recover.
But as we age, our sleep architecture begins to shift.
Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep. The amount of deep sleep for mature adults declines steadily – making sleep more fragmented and less restorative, even if you’re getting enough hours.
At the same time, the circadian rhythm, your body’s internal clock, becomes less stable. Many people experience a shift known as phase advance, feeling sleepy earlier in the evening and waking earlier in the morning, often before they’ve had adequate rest. Hormonal shifts, especially for women during perimenopause and menopause, also contribute to this disruption.
These changes don’t just impact how rested you feel – they affect your long-term health.
Deep, uninterrupted sleep is strongly linked to healthy ageing and longevity. It influences immune resilience, hormone balance, metabolic function, and even how efficiently the brain clears out waste through the glymphatic system.
When sleep becomes shallow or inconsistent, the body’s ability to repair, regulate, and renew itself also begins to decline.
To counter these changes, many people turn to over-the-counter melatonin or prescription sedatives (often referred to as sleeping pills) or antihistamines.
But most of these solutions work by artificially sedating the brain, and may cause more harm than good – particularly as we age.
Melatonin is a hormone your brain produces in response to darkness. It signals that it’s time to wind down – but it doesn’t control how long you sleep or how deeply you rest. When taken in high doses, at the wrong time, or for extended periods, melatonin can:
Sedatives go a step further by suppressing brain activity altogether – inducing unconsciousness, but not true sleep. These drugs can interrupt your brain’s natural sleep architecture, preventing you from reaching slow-wave and REM sleep – the very stages responsible for memory consolidation, emotional regulation, and immune function.
Over time, the use of sedatives has also been linked to increased risk of cognitive decline, particularly in older adults.
Instead of forcing sleep, the goal should be to support the systems that naturally regulate it – including your circadian rhythm, nervous system, cortisol cycles, and neurotransmitters like GABA and serotonin.
This is what allows the body to access real, uninterrupted sleep and with it, the recovery, clarity, and long-term resilience it was designed for.
A hormone-free, science-backed approach to deeper, more restorative sleep.
Unlike most sleep supplements that rely on melatonin or sedatives to force sleep, we intentionally designed Sereniser to support your body’s natural sleep-wake cycle – without disrupting your hormones, creating dependency, or leaving you drowsy the next day.
Formulated with leading longevity researchers in Switzerland, it takes a multi-pathway approach grounded in neuroscience, adaptogens, and chronobiology. Each ingredient was selected for its ability to target key systems involved in high-quality sleep – mood regulation, cortisol balance, circadian rhythm, and sleep architecture – without interfering with your body's natural rhythms.
What makes the Sereniser different:
1. Calms the body and mind
The Sereniser helps ease the physiological and mental tension that can keep you alert, even when you feel tired.
2. Supports deep, uninterrupted sleep
Rather than simply sedating the brain, Sereniser helps the body reach and maintain deep, restorative sleep stages.
3. Balances your internal rhythm
Rather than flooding the system with synthetic melatonin, Sereniser helps regulate your body's own circadian rhythm to promote consistency and better mornings.
4. Non-habit forming & melatonin-free
Many sleep supplements rely on synthetic melatonin, which can disrupt your natural rhythm and lead to dependency over time. Sereniser takes a more natural, longer-term approach:
Just deep, consistent rest - the way your body was designed to experience it.
Women experience sleep differently – and this becomes especially noticeable during perimenopause and menopause. Despite maintaining consistent routines, many begin to experience new or worsening sleep disruptions: difficulty staying asleep, early morning awakenings, or waking feeling less restored than before.
These changes are not imagined – they’re physiological.
As estrogen and progesterone begin to decline, they also influence the release and amount of other hormones and neurotransmitters that regulate sleep:
When these hormones and neurotransmitters are thrown out of balance, sleep becomes lighter, more fragmented, and more easily disrupted. Hot flashes, increased nighttime cortisol, and changes in thermoregulation all add to the challenge – even for women who’ve never struggled with sleep before.
Sleep during menopause is also more sensitive to stress, screen exposure, diet, and even small environmental changes. The nervous system becomes more reactive, and the body may cycle in and out of sleep stages more frequently.
But these shifts go beyond night-time rest.
Because deep sleep plays a key role in hormone regulation, immune resilience, and cognitive repair, a decline in sleep quality during menopause can also impact long-term energy, clarity, and healthy ageing.
And yet, most sleep solutions aren’t designed with women in mind — let alone with the complexity of hormonal transitions.
Understanding the root causes of disrupted sleep in midlife is essential to supporting better rest – and better health – for decades to come.
Feel the dıfference
The Sereniser features a powerful blend of clinically backed ingredients – including Safr’Inside™, Holixer™, Serezin™, L-theanine, Magnesium Bisglycinate, and Vitamin B6 – that work together to support natural sleep rhythms, balance cortisol, and restore deep, uninterrupted sleep without sedation or habit-forming effects.
Take 2 capsules per day, preferably 1 to 2 hours before bedtime.
Manufactured in Switzerland
Formulated by Experts
Sustainable Packaging
Clinically proven results
Vegan
Halal
Active ingredients:
Green Tea Extract 333mg of which L-Theanine 200mg, Blend of Frankincense and Ginger Extract (Serezin™) 300mg, Holy Basil Extract (Holixer™) 250mg, Magnesium (from Magnesium Bisglycinate) 56.25mg, Saffron Extract (Safr’Inside™) 30mg, Vitamin B6 (Pyridoxal 5-Phosphate) 1.4mg
Other ingredients:
At AVEA, we prioritise transparency and quality. We manufacture in Switzerland and source globally, focusing on ingredients with excellent bioavailability and high activity through standardised plant extracts. Every batch is rigorously double-tested for purity by an independent Swiss lab. We go beyond standard labelling to provide detailed information, and our customer service team is available for any questions or test result requests.
| Active ingredients | Supplier | Production method |
|---|---|---|
| Green Tea Extract with L-Theanine | JiangXi Nanyu Biotechnology Co., Ltd. | Camellia sinensis leaf extraction |
| Blend of Frankincense and Ginger Extract (Serezin™) | Laila Nutraceuticals Ltd. | Boswellia serrata gum-resin and Zingiber officinale rhizome extraction |
| Holy Basil Extract (Holixer™) | Vivatis Pharma GmbH | Ocimum tenuiflorum leaf extraction |
| Magnesium Bisglycinate (Magnesium) | Nutraceuticals Group Europe Ltd. | Chemical synthesis |
| Saffron Extract (Safr’Inside™) | ACTIV'INSIDE | Crocus sativus stigma extraction |
| Pyridoxal 5-Phosphate (Vitamin B6) | ECSA Chemicals AG | Chemical synthesis |
We ship worldwide, free delivery above 50£/€/CHF, 5-10 days from dispatch depending on your region.
The Sereniser combines clinically studied plant extracts like Safr’Inside™, Holixer™, and Serezin™ with L-theanine, Magnesium Bisglycinate, and Vitamin B6 to support natural sleep rhythms by balancing cortisol, enhancing GABA and serotonin, and restoring deep, uninterrupted rest.
A standardised, patented, and highly bioavailable saffron extract shown to reduce the time it takes to fall asleep, improve sleep quality, and ease anxious thoughts – by supporting the conversion of serotonin to melatonin and helping balance cortisol levels.
A clinically studied extract from Holy Basil that helps balance cortisol, reduce stress, and activate the parasympathetic nervous system – promoting deeper rest and calmer nights.
A targeted blend of Ginger and Frankincense extracts, designed to support deep, restorative sleep by reducing nighttime discomfort – helping you wake up feeling refreshed and renewed.
A naturally occurring amino acid found in green tea that promotes a calm, focused state without sedation. By supporting alpha brain wave activity, it helps quiet mental overstimulation and eases you into sleep – even after a stressful day.
Magnesium is also naturally found in foods like sunflower seeds. We use a highly bioavailable form: magnesium bisglycinate. Bound to glycine, a calming amino acid, it's especially gentle on the stomach and highly effective.
An essential co-factor in the production of GABA and serotonin – two key neurotransmitters that regulate mood and sleep. Also found in seeds and nuts, it supports a balanced circadian rhythm and helps enhance your body’s resilience to stress.
Manufactured in Switzerland
Formulated by experts
Sustainable Packaging
Clinically proven results
Vegan
Halal
The Sereniser is a melatonin-free sleep supplement designed to help you fall asleep faster, stay asleep longer, and wake up refreshed by supporting your body’s natural sleep rhythm.
You may notice it’s easier to unwind in the evening, fall asleep faster, and feel more relaxed at night as your stress levels begin to balance out.
Falling asleep becomes easier, nighttime wake-ups occur less frequently. Your sleep becomes more continuous – so you wake up feeling noticeably more rested and balanced.
Nighttime wake-ups become less frequent, sleep feels deeper and more restorative, and you start waking up with greater mental clarity and lasting energy.
* Based on clinical data. Individual results may vary.
Here is what they love about the Sereniser:
Not at all. The Sereniser is made with clinically studied plant extracts that support your body’s natural sleep systems. There are no sedatives or hormones, and no risk of rebound effects if you decide to stop.
While melatonin can help with short-term issues like jet lag, it doesn’t address the root causes of poor sleep and may disrupt your natural sleep architecture. It can lead to fragmented sleep, grogginess, and even reduced natural melatonin production with long-term use.
AVEA's Sereniser supports your body’s own melatonin production while also addressing key sleep disruptors like stress, inflammation, and cortisol imbalance. This promotes faster sleep onset, deeper rest, and refreshed mornings – without dependency or side effects.
Take 2 capsules with water around 1-2 hours before bedtime. If you’re sensitive to supplements, you can start with 1 capsule for a few nights and adjust as needed.
The Sereniser doesn’t knock you out. Instead, it works gradually by calming the nervous system, easing mental tension, and supporting natural melatonin production – so you may begin to feel more relaxed and ready for bed, not suddenly drowsy.
No. The Sereniser is melatonin-free and non-sedating, so it won’t interfere with your natural sleep architecture. Most users wake up feeling clear-headed, refreshed, and well-rested.
Some people notice changes in the first few nights – like falling asleep faster or waking up less. But clinical studies on the Sereniser’s ingredients show the most noticeable benefits within 2 to 4 weeks of consistent use.
Your product will be dispatched from our UK warehouse within 24 hours.
We ship internationally and offer multiple shipping options:
We offer FREE shipping from an order value of £50 through postal route as well as faster shipping options through commercial routes, depending on the destination country. Shipping options with estimated delivery time and final cost are calculated and shown during checkout.
If your country is not part of our shipping destinations, contact our customer service (support@avea-life.com) and we will look into our options.
The Sereniser is generally well-tolerated and can be taken alongside other supplements. However, if you’re using prescription medications for sleep, anxiety, or depression, we recommend speaking with your healthcare provider first.
The full benefits of supplements take time to develop. Many customers notice initial improvements within the first month, while the full effect typically unfolds after 2-3 months. Since everyone is unique, results may vary. That’s why we recommend following your new routine for at least 3 months. If you’re not satisfied after this period, you can make use of our 90-day money-back guarantee.
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