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4.6/5 based on over 600 ratings

Sereniser

The Sereniser is your non-hormonal solution to truly restorative sleep – helping you fall asleep faster, stay asleep longer, and wake up clear-headed and energised. Its clinically studied ingredients calm the mind, promote deeper, uninterrupted sleep, and regulate natural sleep cycles, ensuring you wake up recharged and ready for the day.

  • Fall asleep faster – feeling calm and relaxed
  • Sleep deeper for longer – with uninterrupted, restorative rest
  • Wake up refreshed – thanks to optimised sleep quality
  • Start your day clear and energised – with no grogginess or fog
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5 reasons to incorporate AVEA’s Sereniser into your daily habits

Fall asleep faster – naturally

The Sereniser gently calms your nervous system and eases mental tension, helping you fully unwind and drift off into restful sleep with ease.

Sleep deeper and stay asleep longer

Do you often wake up in the middle of the night? The Sereniser supports uninterrupted, restorative sleep by reducing restlessness and enhancing deep sleep cycles.

Wake up refreshed, not groggy

With deeper, more consistent sleep each night, you’ll start your day with steady energy, better focus, and a clearer mind.

Reset your natural sleep rhythm

Whether you're dealing with late nights, jet lag, or inconsistent routines, the Sereniser helps restore a healthy sleep-wake cycle.

Your defence against modern sleep disruptors

From stress and screen time to irregular schedules, the Sereniser targets the root causes of poor sleep in today’s world.

Sleep science 101

The science behind deep, restorative sleep

Sleep is not just about duration – it’s about depth, cycles, and consistency.

Most of us know we need 7–9 hours of sleep, but not all sleep is created equal.

Throughout the night, your brain moves through a series of stages—light sleep, deep sleep (also known as slow-wave sleep), and REM sleep (when most dreaming occurs).  These stages cycle roughly every 90 minutes and each plays a distinct role in how your body and mind recover.

  • Light sleep helps the body relax and stabilise, preparing for deeper, restorative sleep stages.
  • Deep sleep is when the body repairs muscle, restores energy, and strengthens the immune system.
  • REM sleep supports memory consolidation, emotional processing, and cognitive performance.

But as we age, our sleep architecture begins to shift.

Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep. The amount of deep sleep for mature adults declines steadily – making sleep more fragmented and less restorative, even if you’re getting enough hours.

At the same time, the circadian rhythm, your body’s internal clock, becomes less stable. Many people experience a shift known as phase advance, feeling sleepy earlier in the evening and waking earlier in the morning, often before they’ve had adequate rest. Hormonal shifts, especially for women during perimenopause and menopause, also contribute to this disruption. 

These changes don’t just impact how rested you feel – they affect your long-term health.

Deep, uninterrupted sleep is strongly linked to healthy ageing and longevity. It influences immune resilience, hormone balance, metabolic function, and even how efficiently the brain clears out waste through the glymphatic system.

When sleep becomes shallow or inconsistent, the body’s ability to repair, regulate, and renew itself also begins to decline.

Feel the dıfference

Improve your sleep with the Sereniser and wake up truly rested, fully recharged, and ready to take on the day.

93%

reported overall better sleep quality*

easier to wake up in the morning*

37%

experienced reduced stress & cortisol levels after 8 weeks**

4

weeks for significantly improved sleep quality***
* PLT Health, 2023 (Serezin™ clinical study). ** Frontiers in Nutrition, 2022 (Holixer™ clinical trial). *** Lang et al., medRxiv, 2025 (Safr’Inside™ clinical study).

Sereniser

Supports restful sleep
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Discover the science behind the Sereniser

The Sereniser combines clinically studied plant extracts like Safr’Inside™, Holixer™, and Serezin™ with L-theanine, Magnesium Bisglycinate, and Vitamin B6 to support natural sleep rhythms by balancing cortisol, enhancing GABA and serotonin, and restoring deep, uninterrupted rest.

Safr’Inside™

A standardised, patented, and highly bioavailable saffron extract shown to reduce the time it takes to fall asleep, improve sleep quality, and ease anxious thoughts – by supporting the conversion of serotonin to melatonin and helping balance cortisol levels.

Holixer™

A clinically studied extract from Holy Basil  that helps balance cortisol, reduce stress, and activate the parasympathetic nervous system – promoting deeper rest and calmer nights.

Serezin™

A targeted blend of Ginger and Frankincense extracts, designed to support deep, restorative sleep by reducing nighttime discomfort – helping you wake up feeling refreshed and renewed.

L-Theanine

A naturally occurring amino acid found in green tea that promotes a calm, focused state without sedation. By supporting alpha brain wave activity, it helps quiet mental overstimulation and eases you into sleep – even after a stressful day.

Magnesium Bisglycinate

Magnesium is also naturally found in foods like sunflower seeds. We use a highly bioavailable form: magnesium bisglycinate. Bound to glycine, a calming amino acid, it's especially gentle on the stomach and highly effective.

Vitamin B6

An essential co-factor in the production of GABA and serotonin – two key neurotransmitters that regulate mood and sleep. Also found in seeds and nuts, it supports a balanced circadian rhythm and helps enhance your body’s resilience to stress.

Natural ingredients
Recommended by longevity experts
Made in Europe
Clinically proven results

What can you expect?

The Sereniser is a melatonin-free sleep supplement designed to help you fall asleep faster, stay asleep longer, and wake up refreshed by supporting your body’s natural sleep rhythm.

1. MONTH

Improved relaxation, reduced stress

You may notice it’s easier to unwind in the evening, fall asleep faster, and feel more relaxed at night as your stress levels begin to balance out.

2. MONTHS

More restful, uninterrupted nights

Falling asleep becomes easier, nighttime wake-ups occur less frequently. Your sleep becomes more continuous – so you wake up feeling noticeably more rested and balanced.

3. MONTHS

Deeper, more restorative sleep

Nighttime wake-ups become less frequent, sleep feels deeper and more restorative, and you start waking up with greater mental clarity and lasting energy.


* Based on clinical data. Individual results may vary.

Why choose AVEA?

Frequently asked questions

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Rest deeper, rise stronger. The natural way to sleep better.

Get the rest you deserve. The Sereniser™ is a science-backed formula with innovative plant extracts that supports deep, restorative sleep and calm nights – without dependency.

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