Stimulates your body’s own collagen production.
A patented, 100% vegan formula developed with leading longevity experts in Switzerland, designed to stimulate your body’s own natural collagen production from within.
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Collagen Activator
Based on breakthrough research conducted at ETH Zurich and now published in Natures npj Aging, we developed a more effective way to replenish the body's natural collagen levels. The Collagen Activator features Colgevity™ - our patented, 100% vegan collagen precursor complex developed in partnership with leading longevity scientists at ETH Zurich.
Unlike traditional animal-derived collagen peptides which must be broken down into smaller fragments before your body can utilise them, our formula provides the optimised building blocks to boost the body’s collagen regeneration for deeper, longer lasting results. The Collagen Activator:
- Helps the body replenish its collagen levels with a patented formula discovered at ETH Zurich to counteract age-related collagen decline
- Has been clinically shown to improve elasticity and firmness, helping visibly reduce fine lines and early signs of skin ageing
- Boosts skin hydration and smoothness, supporting a more radiant, youthful complexion
- Strengthens hair and nails with targeted micronutrients essential for keratin structure
- Backed by a peer-reviewed study in Nature’s npj Aging showing superior performance vs. traditional collagen
Manufactured in Switzerland
Based on cutting-edge research
Try without risk
90 days money back guarantee
Advanced Collagen Stimulation
Improved Texture & Firmness
Powered by Colgevity™ - our patented, plant-based collagen precursor shown to be up to 4x more effective than generic collagen - this formula stimulates your body’s own collagen production for deeper, longer-lasting results.
Powered by Colgevity™ - our patented, plant-based collagen precursor shown to be up to 4x more effective than generic collagen - this formula stimulates your body’s own collagen production for deeper, longer-lasting results.
With Alpha-Ketoglutarate (AKG) and Vitamin C from Acerola Cherry, this synergistic formula supports collagen synthesis and improves skin firmness. Astaxanthin, a powerful antioxidant from microalgae, helps protect against oxidative stress, enhancing skin texture and tone.
Lasting Hydration & Elasticity
Stronger Hair & Nails
Collagen provides the structural framework that holds hyaluronic acid and prevents moisture loss. By restoring collagen levels, the Collagen Activator helps skin retain hydration more effectively - improving elasticity, glow, and firmness, while reducing two key signs of ageing: dryness and collagen breakdown.
Collagen provides the structural framework that holds hyaluronic acid and prevents moisture loss. By restoring collagen levels, the Collagen Activator helps skin retain hydration more effectively - improving elasticity, glow, and firmness, while reducing two key signs of ageing: dryness and collagen breakdown.
Collagen is essential not just for skin, but also for the structural integrity of hair and nails. The Collagen Activator helps reinforce keratin-rich tissues, promoting thicker, shinier hair and stronger, less brittle nails.
Advanced Collagen Stimulation
Powered by Colgevity™ - our patented, plant-based collagen precursor shown to be up to 4x more effective than generic collagen - this formula stimulates your body’s own collagen production for deeper, longer-lasting results.
Improved Texture & Firmness
With Alpha-Ketoglutarate (AKG) and Vitamin C from Acerola Cherry, this synergistic formula supports collagen synthesis and improves skin firmness. Astaxanthin, a powerful antioxidant from microalgae, helps protect against oxidative stress, enhancing skin texture and tone.
Lasting Hydration & Elasticity
Collagen provides the structural framework that holds hyaluronic acid and prevents moisture loss. By restoring collagen levels, the Collagen Activator helps skin retain hydration more effectively - improving elasticity, glow, and firmness, while reducing two key signs of ageing: dryness and collagen breakdown.
Stronger Hair & Nails
Collagen is essential not just for skin, but also for the structural integrity of hair and nails. The Collagen Activator helps reinforce keratin-rich tissues, promoting thicker, shinier hair and stronger, less brittle nails.
The role of collagen in skin ageing
Skin Longevity basics
Most conversations around skin ageing acknowledge collagen loss, but few explore what it really means, or the solutions available to address it. Collagen is the body’s primary structural protein which forms the scaffolding which gives skin its firmness, elasticity and smooth texture.
Unfortunately, from our mid-20s, natural collagen production begins to decline by about 1% each year, accelerating in our 40s, and compounded by external stressors such as UV exposure and oxidative damage.
This combination of slowed production and increased breakdown weakens the skin’s internal structure, leading to visible signs of ageing.
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Collagen is one of the most vital structural proteins in the body, responsible for keeping skin firm, elastic, and resilient. Yet most collagen supplements fail to deliver meaningful results - not because collagen doesn’t work, but because it only works if it's provided in a form that the body can actually use.
Traditional collagen products often rely on hydrolysed animal collagen: large protein fragments that must be broken down and absorbed before they can be used by the body. While these peptides can provide raw materials, their biological impact is limited as the body doesn’t automatically recognise them as a signal to produce more collagen, and in many cases, they are diverted to other functions like general protein metabolism, offering little benefit to the skin.
A peer-reviewed study published in Nature’s npj Aging confirms this gap: for collagen renewal to occur, the body requires specific amino acids, in a precise ratio, delivered with the correct biological signal. To effectively trigger collagen synthesis, three elements are essential:
- Precise amino acids:
Collagen is primarily built from three key amino acids: glycine, proline, and hydroxyproline. These must be delivered in the right ratio and form to be recognised as collagen-building material. Generic protein or random peptides won’t achieve the same result. - A biological signal to activate production
Collagen is produced by fibroblasts, which are specialised skin cells that require a biological signal to initiate synthesis. Without this signal, the body has no reason to begin building new collagen, even if the raw materials are present. - Cofactors that stabilise and support synthesis
Nutrients such as vitamin C and Alpha-Ketoglutarate (AKG) are essential for the enzymatic processes that link collagen fibres and stabilise the matrix. Without them, collagen strands remain weak, disorganised, and prone to breakdown.
When these components are missing or imbalanced, the body lacks both the building blocks and the biological instructions needed to produce strong, stable collagen. This is where many supplements fall short - they may supply fragments but fail to engage the skin’s natural regeneration process.
- Precise amino acids:
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We developed the Collagen Activator to address a key limitation in the collagen supplement space: most formulas simply deliver fragmented, animal-derived collagen without addressing whether the body can use it. Instead of relying on passive replacement, our formula is designed to actively stimulate the body’s own collagen-building processes.
Created in collaboration with longevity scientists from ETH Zurich, the Collagen Activator features Colgevity™ - our patented, 100% vegan collagen precursor. Validated in a peer-reviewed study published in Nature’s npj Aging, this formula was shown to stimulate natural collagen production up to 4× more effectively than traditional collagen peptides.
It combines a precise ratio of amino acids with targeted co-factors to drive endogenous collagen production - helping to rebuild the structural proteins that keep skin firm, smooth, and elastic.
And unlike traditional supplements that use hydrolysed collagen from animal sources, the Collagen Activator works across multiple biological pathways to support natural collagen synthesis at the cellular level:
For replenishing diminishing collagen levels
The foundation of the formula is Colgevity™ - a patented vegan collagen precursor that provides the three key amino acids (glycine, proline, and hydroxyproline) in the precise ratio needed for collagen synthesis. Unlike hydrolysed collagen, which is often broken down before reaching the skin, these building blocks are readily used by fibroblasts to produce new collagen more efficiently, thus helping restore skin volume, structure, and strength.For boosting skin elasticity & hydration
Acerola cherry extract, a potent natural source of vitamin C, supports collagen cross-linking and protects skin cells from oxidative damage. Together with Alpha-Ketoglutarate (AKG) - a longevity compound that fuels cellular repair - this duo helps improve skin’s elasticity, promote smoother texture, and restore hydration balance at the structural level.For enhancing skin firmness and reducing fine lines
As collagen production slows, skin begins to lose its firmness and smooth appearance. The Collagen Activator works to restore dermal density by stimulating natural collagen synthesis and reducing inflammation - two critical processes for maintaining tone and preventing the formation of fine lines. The result: visibly firmer, more youthful-looking skin over time.For strengthening hair and nails
The Collagen Activator provides key amino acids such as Proline, which not only support collagen formation but also contribute to the structure of keratin-rich tissues like hair and nails. Combined with nutrients that enhance tissue repair and integrity, it promotes visibly stronger, less brittle nails and thicker, shinier hair, thus offering a holistic approach to beauty and structural health. -
Collagen is essential for maintaining skin firmness, elasticity, and structure, but supporting skin longevity doesn’t stop at collagen production alone.
Our Collagen Activator is designed to stimulate collagen synthesis directly at the source using Colgevity™, a patented vegan precursor that delivers the exact amino acids needed to form new collagen. Combined with key cofactors like Acerola Cherry (Vitamin C), Alpha-Ketoglutarate (AKG), and Astaxanthin, it helps reactivate the skin’s natural ability to rebuild its internal scaffolding - thus restoring firmness, improving texture, and strengthening hair and nails over time.
SkinSpan™, on the other hand, addresses what causes collagen to break down in the first place. As the skin barrier weakens with age, moisture loss increases, cell renewal slows, and collagen becomes more vulnerable to breakdown. SkinSpan™ reinforces the skin barrier, restores deep hydration, and supports regenerative turnover – creating the ideal conditions for preserving collagen and enhancing the effects of collagen-boosting interventions.
Together, these formulas offer a comprehensive approach to skin longevity:
- Collagen Activator supports collagen production and structural renewal
- SkinSpan™ preserves existing collagen, repairs the skin barrier, and promotes healthy skin regeneration
By combining both, you address not just one part of the skin ageing equation, but all of it, thus helping your skin stay firm, smooth, and resilient over time.
While improved collagen levels are essential for maintaining skin firmness, elasticity, and structure, preserving existing collagen is just as important as producing more of it.
clinically backed formula
Clinical studies on the AVEA® Collagen Activator show:
97%
noticed improved skin quality in just 30 days30.2%
increase in skin hydration in just 30 days1.4
year reduction in biological age after 6 months measured with TruMe Labs Biological Age test4x
more effective than standard collagen supplementsDakhovnik, A., Mantovani, M., Knufinke, M.et al.A collagen amino acid composition supplementation reduces biological age in humans and increases health and lifespan in vivo.npj Aging11, 91 (2025). https://doi.org/10.1038/s41514-025-00280-7
Expert-led formulations
Prof. Collin Ewald
Scientist and Professor at ETH Zurich"Collagen molecules are too large to be absorbed directly by the body. With this vegan pre-cursor, Colgevity™, we are telling the body to stimulate its own collagen production for more effective collagen synthesis."
Dr. med. Intan Pramono
Dermatologist, Hautwerk Clinic"Our clinical study found that after a daily intake of the Collagen Activator over a period of 3 months, skin quality significantly improved, measured via Visia Skin Analysis."
Konstantinos Jiouchas, M.D.
Medical Director, Zurich Plastics"AVEA uses a vegan collagen pre-cursor, combined with Vitamin C, AKG and Astaxanthin for more effective results"
Dr. Cherin Dürr
Aesthetic Medicine Expert"For me and my clients, I have noticed a significant improvement in skin health, skin firmness, and skin texture."
Dr. med. Valentina Bänninger
Lead Physician and Co-Founder, Sweet Skin"Collagen is the most important structural protein in our body. As we age, collagen breakdown is more prevalent than collagen renewal. AVEA’s Collagen Activator actively counters this breakdown."
Vegan
Collagen Activator
30 sachets per box
Vegan
Collagen Activator
30 sachets per boxBased on breakthrough research conducted at ETH Zurich and now published in Natures npj Aging, we developed a more effective way to replenish the body's natural collagen levels. The Collagen Activator features Colgevity™ - our patented, 100% vegan collagen precursor complex developed in partnership with leading longevity scientists at ETH Zurich.
Unlike traditional animal-derived collagen peptides which must be broken down into smaller fragments before your body can utilise them, our formula works upstream to activate the body’s own regenerative processes for deeper, longer lasting results:
- Colgevity™ delivers the three essential amino acids - glycine, proline, and hydroxyproline - in the precise ratio required to stimulate collagen synthesis at the cellular level. This patented, 100% vegan complex has been shown to be up to 4x more effective than standard collagen peptides.
- Acerola Cherry Extract provides a potent, highly bioavailable source of natural vitamin C – essential for collagen production – while helping protect against oxidative stress and support skin smoothness.
- Alpha-Ketoglutarate (AKG) is a longevity-associated molecule that supports cellular energy metabolism and natural collagen formation. It also helps reduce inflammation and promote tissue repair.
- Astaxanthin, one of the most powerful antioxidants found in nature, is derived from microalgae. It helps protect the skin from UV-induced damage and oxidative stress, which are both major contributors to collagen breakdown and premature ageing.
Together, these ingredients work in synergy to stimulate natural collagen production, restore firmness and elasticity – while also supporting stronger hair and nails over time.
90 days money-back guarantee
Take one daily Collagen Activator sachet dissolved in a glass of water, smoothie or yoghurt, preferably after a meal or 1–2 hours before bed to promote skin rejuvenation and support restorative sleep thanks to its Glycine content.
Manufactured in Switzerland
Formulated by Experts
Sustainable Packaging
Clinically proven results
Vegan
Halal
Active ingredients: Colgevity™ 8,400 mg (L-glycine 5,000 mg, L-hydroxyproline 1,700 mg, L-proline 1,700 mg), Calcium Alpha-ketoglutarate 1,000 mg, Algae Powder 200 mg (as Astaxanthin 4 mg), Acerola fruit juice extract 150 mg (provides vitamin C 48 mg)
Other ingredients:
- Silicon dioxide as anti-caking agent to ensure the powder’s free-flowing nature, improve manufacturing processes, maintain ingredient uniformity and enhance the stability of the final product
- Citric acid as acidity regulator to stabilize pH, enhance flavor, improve solubility, prevent microbial growth and protect the product’s active ingredients, ensuring a high-quality and enjoyable final product
- Steviol glycosides from stevia as sweetener to serve as a natural, calorie-free sweetener that enhances the taste, masks unpleasant flavors and improves the palatability of drinks while being suitable for various dietary preferences and restrictions
- Natural raspberry flavours as flavour to enhance taste, mask unpleasant notes, improve consumer appeal and encourage regular consumption of the product (included only in Collagen Activator Lemon Raspberry)
- Peppermint oil powder as flavour to improve taste, mask undesirable flavors, provide a refreshing cooling effect and enhance the sensory experience (included only in Collagen Activator Lemon Raspberry)
- Safflower concentrate (carthamus) as colouring food to enhance visual appeal, standardize product appearance and align with consumer preferences for clean-label, plant-based ingredients (included only in Collagen Activator Lemon)
- Natural lemon flavour as flavour to enhance taste, mask unpleasant notes, improve consumer appeal and encourage regular consumption of the product (included only in Collagen Activator Lemon)
Our formulations are based on cutting-edge Longevity research. Led by Chief Science Officer Sophie Chabloz, our team collaborates with longevity experts from top institutions to create highly effective, science-backed products.
At AVEA, we prioritise transparency and quality. We manufacture in Switzerland and source globally, focusing on ingredients with excellent bioavailability and high activity through standardised plant extracts. Every batch is rigorously double-tested for purity by an independent Swiss lab. We go beyond standard labelling to provide detailed information, and our customer service team is available for any questions or test result requests.
| Active ingredients | Supplier | Production method |
|---|---|---|
| L-Glycine | Xi'an SLT Biotech Co., Ltd. | Chemical synthesis |
| L-Hydroxyproline | Xi'an SLT Biotech Co., Ltd. | Glucose Fermentation |
| L-Proline | Xi'an SLT Biotech Co., Ltd. | Corn fermentation |
| Calcium Alpha-Ketogluterate | Botanic Healthcare Pvt Ltd. | Chemical synthesis |
| Algae Powder | Healthpath Ltd. | Algae fermentation |
| Acerola Fruit Juice Extract | Vidya Herbs Pvt. Ltd. | Acerola fruit juice extraction |
Worldwide shipping, free shipping on orders over £50/€50/CHF50, 3–5 day delivery time.
Collagen Activator
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Clean, transparent, scientifically-backed ingredients from Switzerland.
Formulated with traceable, clinically studied ingredients. Developed and manufactured in Switzerland.
Third-party test results
Colgevity™
8400 mgDeveloped through years of research at ETH Zurich, and now validated in a published clinical study in Nature’s npj Aging, Colgevity™ is our patented, 100% vegan collagen precursor designed to deliver the precise 3:1:1 amino-acid ratio - glycine, proline, hydroxyproline- your body naturally uses to build collagen fibres. Colgevity™ has been shown to activate collagen production up to 4× more effectively than traditional animal-derived collagen supplements.
Acerola cherry extract
150 mg (Providing 48 mg Vitamin C)Acerola cherry extract is one of nature’s richest sources of vitamin C, a vital nutrient essential for the body’s collagen production. Acerola extract protects the skin from oxidative stress, supports skin cell health, and helps keep the skin smooth and resilient⁴.
Alpha-Ketoglutarate (AKG)
1000 mg (Providing 195 mg Calcium)AKG is a key molecule in cellular metabolism, naturally found in small amounts in protein-rich foods. It supports collagen synthesis, helps reduce inflammation, and promotes cellular self-repair by combating oxidative stress³.
Astaxanthin
200 mg (Providing 4 mg Astaxanthin)As one of nature’s most powerful antioxidants, Astaxanthin reduces inflammation and helps protect the skin from oxidative stress², especially from UV damage. Astaxanthin, typically found in microalgae, also preserves collagen by blocking collagen-degrading enzymes and enhances the skin’s defences against environmental damage.
Third-party test results
See full supplement facts
Third-party test results
Manufactured in Switzerland
Formulated by scientists
Sustainable Packaging
Clinically proven results
Vegan
Halal
Expected benefits
Colgevity™ is a patented vegan collagen precursor which effectively boosts collagen production, with ETH Zurich studies showing superior conversion compared to conventional supplements. The changes can be measured using VISIA® skin analysis technology, which tracks improvements in texture and hydration.
After 1 month:
Improvement in skin texture and hydration
Enjoy visibly smoother, more hydrated skin in just one month. Experience a healthy glow, improved moisture levels, and notice stronger nails and hair.
After 3+ months:
Feel more confident in your skin
Users report noticeable improvements in overall skin quality, including smoother-looking fine lines and wrinkles. Often hair and fingernails start to grow faster.
After 9+ months
Youthful skin, hair, nails & joints
Collagen levels in cells are now at a more youthful level. Firmer skin, stronger hair and nails and even improved joint mobility are the typical results seen at this stage.
*Based on customer surveys and scientific literature. Results may vary.
More than 30,000 positive reviews from our Longevity Community
More than 30,000 happy AVEA customers
This is what they love about the Collagen Activator:
Patented formula made in Switzerland.
Collagen source
Hydration
Skin Texture
Efficacy & Absorption
Added Co-Factors
Longevity Benefits
Scientific Integrity
Purity & Clean Label
Traceable Ingredients
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Traditional collagen supplements typically use hydrolysed animal collagen - large protein fragments that must be digested before the body can use them. While they provide generic amino acids, they do not reliably activate collagen production and often lack the biological signals and cofactors needed for true collagen synthesis.
Our Collagen Activator has been developed based on breakthrough research conducted at ETH Zurich and now published in Natures npj Aging, where scientists have discovered a more effective way to replenish the body's natural collagen levels.It features Colgevity™ - our patented, 100% vegan collagen precursor that delivers the exact three amino acids (glycine, proline, hydroxyproline) in the precise 3:1:1 ratio shown in the peer-reviewed study, clinically proven to be up to 4x more effective than standard collagen peptides.
To support full collagen synthesis, the formula also includes essential cofactors such as Vitamin C, AKG, and Astaxanthin, which help stabilize collagen fibres, fuel cellular repair, and protect the skin from oxidative stress. It is a clean, toxins and sugar-free formula, naturally sweetened with Stevia, and made with traceable, clinically dosed ingredients for maximum effectiveness.
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Take one daily Collagen Activator sachet dissolved in a glass of water, smoothie or yoghurt, preferably after a meal or 1-2 hours before bed to promote skin rejuvenation and support restorative sleep thanks to its Glycine content.
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The Collagen Activator is designed to help rebuild and maintain the structural proteins that give your skin its firmness, smoothness, and elasticity. Rather than just replacing collagen with generic peptides, it supports your body’s natural ability to produce more collagen - resulting in visibly firmer skin, fewer fine lines, and improved hydration.
It also strengthens hair and nails, thanks to its amino acid-rich formula and targeted micronutrients that support keratin production and tissue repair. It’s a holistic formula designed not just for beauty, but for skin health and longevity.
In an observational human trial with 58 participants (39 women and 19 men), users reported noticeably healthier, more radiant skin within just a few weeks. After only 30 days, 97% noticed an improvement in overall skin quality, and 83% experienced better skin hydration, clear signs of enhanced skin function and moisture balance.
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Collagen plays a critical role in maintaining skin structure, elasticity, and resilience. As collagen levels decline with age, the skin begins to lose firmness and moisture, leading to fine lines, dullness, and sagging.
The Collagen Activator helps reverse this decline by supplying the exact building blocks (glycine, proline, hydroxyproline) in the right ratio, while also activating fibroblasts - the skin cells responsible for collagen production. Ingredients such as Astaxanthin protect the skin from oxidative damage, and AKG fuels cellular repair. Together, they help rebuild the skin’s internal scaffolding for a firmer, smoother, and more radiant complexion over time.
We’ve put together our top read articles on collagen below:
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Yes, unlike most collagen supplements in the market, our Collagen Activator is a 100% vegan supplement that does not contain any animal-derived ingredients.
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Yes, all of our supplements target different biological drivers of ageing and the Collagen Activator was designed to work synergistically with other AVEA supplements as part of a comprehensive longevity routine.
- SkinSpan™ - While the Collagen Activator stimulates collagen production, SkinSpan™ helps protect the collagen you already have. It reinforces the skin barrier, replenishes hydration, and supports cellular renewal - all of which are essential for maintaining firm skin over time and supporting skin longevity comprehensively.
- Essentials – This foundational multivitamin ensures your body gets optimal levels of key micronutrients - including zinc, selenium, and vitamin A - which play an important role in collagen metabolism, immune support, and overall skin and cellular health.
- Vitality Bundle (NMN + Booster) – Collagen production is an energy-intensive process. The Vitality Bundle helps restore NAD⁺ levels and mitochondrial function, ensuring your cells have the energy they need to synthesise collagen, repair damage, and support healthy ageing from within.
- Biomind – Chronic inflammation and gut imbalance can impair collagen production and accelerate skin ageing. Biomind supports a healthy gut-brain axis and reduces systemic inflammation, creating a more favourable internal environment for skin regeneration and health.
Together, these formulations provide comprehensive support from internal rejuvenation to visible improvements in skin firmness, elasticity, and glow.
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Yes, all ingredients in AVEA products are clinically tested and proven safe.
Each active compound – whether in the Collagen Activator or other formulations – is backed by scientific studies that confirm both efficacy and safety. We carefully select the purest and most bioavailable plant extracts and compounds available. Our product descriptions clearly outline the production methods and origins of each ingredient.
AVEA manufactures in state-of-the-art, GMP-certified facilities that are regularly audited by Swiss authorities. Each product batch is sent to an independent Swiss laboratory for additional purity testing, ensuring the highest quality and safety.
The Collagen Activator is free from unnecessary additives – carefully developed to support your long-term health and skin from within.
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At AVEA, every formulation begins with a deep understanding of the biological processes that drive ageing and longevity – and how we can influence them. Our work is grounded in the latest findings from the fields of cellular health, metabolic and longevity science.
Led by our Co-Founder and Chief Science Officer, Sophie Chabloz, our in-house science team partners with world-class longevity researchers and biotech experts from leading academic institutions. Together, we translate complex, peer-reviewed research into targeted, effective supplement formulas designed to support cellular function, resilience, and long-term vitality.
Each supplement we create is based on clinically studied ingredients, optimised for bioavailability, and rigorously tested — so that what works in the lab also works in your daily life.
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Your supplements will be dispatched from our UK warehouse within 24 hours.
We ship internationally and offer a variety of shipping options:
Standard shipping is free for orders over £50 and is sent via local postal services. For faster delivery, we also offer express options via commercial carriers, depending on your destination.All available shipping methods — along with estimated delivery times and final costs — will be displayed during checkout.
If your country isn’t listed at checkout, feel free to contact our customer service
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The full benefits of supplements take time to develop. Many customers notice initial improvements within the first month, while the full effect typically unfolds after 2–3 months. Since everyone is unique, results may vary. That’s why we recommend following your new routine for at least 3 months.
If you’re not satisfied after this period, you can make use of our 90-day money-back guarantee.
Frequently asked questions
The AVEA Promise
Scientific References
Kohandel, Z., Farkhondeh, T., Aschner, M., Pourbagher-Shahri, A. M., & Samarghandian, S. (2022). Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 145, 112179. https://doi.org/10.1016/j.biopha.2021.112179
Manzanares, S., Arias, E.J., Floriach, N., M., S., & Roldán, F.A. (2021). Synergistic antiaging and Dermal Restorative Effects of an Oral Bioactive Procollagen and Astaxanthin Supplement with A Topical Retinyl Palmitate, Vitamin C, Hyaluronic Acid and Alpha Hidroxy Acid Based Regimen. Journal of Dermatology Research. 10.1016/j.biopha.2021.112179
Son, E. D., Choi, G. H., Kim, H., Lee, B., Chang, I. S., & Hwang, J. S. (2007). Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice. Biological & pharmaceutical bulletin, 30(8), 1395–1399. https://doi.org/10.1248/bpb.30.1395
DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthopaedic journal of sports medicine, 6(10), 2325967118804544. https://doi.org/10.1177/2325967118804544
Al-Atif H. (2022). Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics. Dermatology practical & conceptual, 12(1), e2022018. https://doi.org/10.5826/dpc.1201a18
Alvarez-Suarez, J. M., Giampieri, F., Gasparrini, M., Mazzoni, L., Santos-Buelga, C., González-Paramás, A. M., Forbes-Hernández, T. Y., Afrin, S., Páez-Watson, T., Quiles, J. L., & Battino, M. (2017). The protective effect of acerola (Malpighia emarginata) against oxidative damage in human dermal fibroblasts through the improvement of antioxidant enzyme activity and mitochondrial functionality. Food & function, 8(9), 3250–3258. https://doi.org/10.1039/c7fo00859g