Effective senolytics combine multiple strategies to reduce harmful “zombie” cells. Ideally, a senolytic both promotes the removal of existing senescent cells and prevents the accumulation of new ones.
AVEA’s Cell Primer combats senescent cells through 3 powerful mechanisms:
1. Targeted removal of senescent cells with natural senolytics
Quercetin and Fisetin, plant compounds found in apples and strawberries, are natural senolytics that activate pathways leading to apoptosis (programmed cell death) in harmful senescent cells. Research shows that clearing these cells can reduce inflammation, accelerate recovery, and support healthy cellular renewal.
2. Preserving healthy cells and slowing premature senescence
PQQ (Pyrroloquinoline Quinone), a compound found in vegetables like spinach and celery, supports mitochondrial function and reduces oxidative stress – two key factors in preventing the formation of new senescent cells. By maintaining cellular health, PQQ may help prevent metabolic decline and premature ageing.
3. Supporting cellular repair and regeneration
Spermidine, a naturally occurring polyamine, stimulates autophagy – a crucial process by which cells recycle and repair damaged components. Enhanced autophagy helps preserve cell function and resilience, reducing the buildup of damage associated with ageing and chronic inflammation.
