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NMN SCIENCE

NMN is an essential building block of NAD+.

NMN targets the natural decline of NAD+ in our bodies as we age to support vibrant health.

WHAT IS NMN?

NMN is a potent NAD+ precursor.

NMN, short for nicotinamide mononucleotide, is a naturally occurring vitamin B3 derivative and a building block, known as a precursor, of NAD+ (nicotinamide adenine dinucleotide). NAD+ is an essential coenzyme present in all living cells that plays a role in protecting us from the effects of ageing and disease. But, unfortunately, NAD+ declines as we age.

That’s where NMN comes in. By targeting the natural decline of NAD+ in our bodies, NMN replenishes NAD+ levels and helps you maintain vibrant health for longer.

At Avea, our NMN supplement is a powerful high-quality formulation that targets the diverse mechanisms of ageing at the cellular level. Our supplement is third-party tested for purity and contains Uthever® NMN, a brand recognized for its top quality and safety, as well as less temperature sensitivity and more bioavailability than other NMN brands.

Our NMN supplement has shown promising results in a recent randomised, double-blind, controlled clinical trial to evaluate its efficacy and safety.

NMN AND NAD+ LONGEVITY

NMN replenishes NAD+ and counteracts the effects of ageing.

NMN AND SCIENTIFIC STUDIES

NMN supplementation effectively targets the signs of ageing.

You can think of NAD+ as a type of fuel that helps many proteins and enzymes in your body carry out essential functions. NNM is a building block of this "fuel," meaning it is needed in order for your body to make NAD+.

NMN

Regain your health, energy, and cellular functions to youthful levels.

Backed by science, NMN is safe and effective at slowing and even reversing ageing, increasing energy, and supporting nearly every organ in the body. Use it on its own or in tandem with the Booster for optimal results.

Shop Our NMN

References

  1. Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell metabolism, 27(3), 529–547. https://doi.org/10.1016/j.cmet.2018.02.011
  2. North, B. J., Rosenberg, M. A., Jeganathan, K. B., Hafner, A. V., Michan, S., Dai, J., Baker, D. J., Cen, Y., Wu, L. E., Sauve, A. A., van Deursen, J. M., Rosenzweig, A., & Sinclair, D. A. (2014). SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. The EMBO journal, 33(13), 1438–1453. https://doi.org/10.15252/embj.201386907
  3. Li, J., Bonkowski, M. S., Moniot, S., Zhang, D., Hubbard, B. P., Ling, A. J., Rajman, L. A., Qin, B., Lou, Z., Gorbunova, V., Aravind, L., Steegborn, C., & Sinclair, D. A. (2017). A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science (New York, N.Y.), 355(6331), 1312–1317. https://doi.org/10.1126/science.aad8242
  4. Kiss, T., Nyúl-Tóth, Á., Balasubramanian, P., Tarantini, S., Ahire, C., Yabluchanskiy, A., Csipo, T., Farkas, E., Wren, J. D., Garman, L., Csiszar, A., & Ungvari, Z. (2020). Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. GeroScience, 42(2), 527–546. https://doi.org/10.1007/s11357-020-00165-5
  5. Yoshino, M., Yoshino, J., Kayser, B. D., Patti, G. J., Franczyk, M. P., Mills, K. F., Sindelar, M., Pietka, T., Patterson, B. W., Imai, S. I., & Klein, S. (2021). Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science (New York, N.Y.), 372(6547), 1224–1229. https://doi.org/10.1126/science.abe9985

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